Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity connected to bortezomib, a proteasome inhibitor Employed in the treatment of various myeloma. Its synthesis or analyze is critical for making certain the purity and safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise varieties of cancer, together with Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is very important for optimizing the manufacturing method and ensuring large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to treat breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the cure of breast cancer. Different intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in treating CAS NO. 571188-59-5 cancers for instance ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the therapy of colorectal cancer and modest cell lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound PMD is linked to the synthesis of adamantane derivatives, that have numerous applications, like antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for form two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of various gluconic acid derivatives, which can be Employed in meals, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to handle kind 2 diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).